339 CONSTANTIUS II`(Roman Empire)
Son of Constantine the Great, declared intermarriage with Jews and the circumcision of heathen or Christian slaves punishable by death. Considering that slaves fueled the economy, this put any Jewish owned businesses into a position where they could not compete – which was one of its goals. He also called synagogues "concliabula" (brothels). This is the first time this term is used.